The intestines of most people are becoming increasingly fragile. If you search for "diarrhea" on the Internet, you will find that many people are troubled by diarrhea. Diarrhea is divided into acute diarrhea and chronic diarrhea. If it is acute diarrhea, it is better to seek medical treatment; if it is long-term and chronic diarrhea, it means intestinal sensitivity, and it is necessary to strengthen intestinal maintenance. Prebiotics are very good things to regulate the intestinal environment.

Long-term diarrhea is actually intestinal dysfunction. Research shows that intestinal dysfunction is closely related to temporary or persistent dysbacteriosis. The human intestine is home to more than 400 species of bacteria. These normal intestinal flora are mainly composed of beneficial bacteria, harmful bacteria and neutral bacteria. The so-called dysbacteriosis means that the balance of the intestinal flora deviates from the potentially beneficial or health-promoting beneficial bacteria and shifts towards the increase of harmful bacteria. While taking probiotics, people can also combine it with mannan oligosaccharide, fructo-oligosaccharides, etc. to provide food for the beneficial bacteria in the intestines to promote their proliferation and development, which is beneficial to the balance of the flora.

MOS is an oligosaccharide composed of D-mannose connected through β-1, 4 glycosidic bonds to form a main chain, and glucose is connected to the main chain or branch chain. It’s degree of polymerization is between 2 and 10. It is a new type of prebiotic that can activate and proliferate a large number of bifidobacteria and lactobacilli, and regulate the microecological balance. MOS has the characteristics of low caloric value, low sweetness, not causing dental caries, and not increasing blood sugar concentration. It is a new generation of functional food.

Advantages of Mannan Oligosaccharides.

1. Prevent intestinal. 

MOS has a unique mannose receptor binding site and preferentially binds to mannose receptors on the surface of human intestinal cells to prevent the adhesion of pathogenic microorganisms to the intestinal mucosal epithelium of animals and achieve the elimination of pathogenic bacteria.

2. Adjust microecological balance.

Mannose is not digested and absorbed in the human gastrointestinal tract and enters the large intestine directly, selectively providing culture substrate for beneficial bacteria such as bifidobacteria in the intestine, quickly stimulating the proliferation of beneficial bacteria, increasing the activity of beneficial bacteria, improving the intestinal microecological environment, and comprehensively improving various physiological functions.

3. Prevent constipation.

Bifidobacteria ferment oligosaccharides to produce a large amount of short-chain fatty acids, which can stimulate intestinal peristalsis, improve intestinal function, increase stool moisture and maintain a certain osmotic pressure, thereby preventing constipation.

4. Prevent obesity.

Oligosaccharides are difficult to be broken down by enzymes in the digestive tract and difficult to be digested and absorbed by the human body. According to measurements, its calorific value is below 1.5cal/g. After being ingested by the human body, it will not cause obesity. At the same time, because it is similar to a kind of water-soluble fiber, it can reduce serum, cholesterol and improve blood lipids.

5. Improve immunity.

Mannan Oligosaccharides are immunogenic, effectively stimulate immune responses, and can bind to the surface of toxins, viruses and fungal cells, enhance cellular and humoral immune responses, and prevent bacteria and diseases.

6. Inhibit cancer cells.

Normal people's fasting gastric juice contains 102 to 105 bacteria. The destruction of normal flora causes damage to the gastric mucosa and causes gastric ulcers. It can also cause the colonization and mass reproduction of Helicobacter pylori, cause gastritis and other precancerous lesions, and thus cause gastric cancer. Manno-oligosaccharides can prevent and treat gastric cancer by regulating the imbalance of gastrointestinal flora (promoting the growth of beneficial bacteria and inhibiting the colonization and reproduction of Helicobacter pylori) and directly killing or inhibiting gastric cancer cells.

7. Remove free radicals.

The occurrence of many diseases is related to lipid peroxidation caused by free radicals. MOS can directly scavenge reactive oxygen free radicals through complex reduction reactions, increase their activity through metabolic pathways in the body, and reduce the MDA (the final metabolite of lipid peroxidation and indirectly reflects the degree of cell damage) content in plasma, liver, small intestine and pancreas, which can prevent, control, or delay the occurrence of diseases.